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It is worth noting that glutathione disulfide is structurally close to both the metal(II)-bis-glutathionato conjugates (GS-M-SG) and to the lanthionine-bound glutathione thioether dimer (G-S-G) produced by nucleophilic attack of the thiolate group of glutathione to the electrophilic carbon of dehydro-alanine (acrylate) glutathione, as shown in Scheme 10

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Brodericksq TL, Quinneys HA, Lopaschukllll GD (1992) Carnitine stimulation of glucose oxidation in the fatty acid perfused isolated working rat heart*

The medication has undergone extensive clinical evaluation through the SUSTAIN trials for diabetes and STEP trials for weight management, establishing both efficacy and safety across diverse patient populations

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